Loop Hero has all sorts of unique card combinations that can improve buffs or create new enemies. Taking advantage of these card synergies is a useful way to get more loot and survive even longer. Read below for every combo we currently know about.
All Card Combinations in Loop Hero
Card/Tile |
Combos |
Notes |
Rocks | Placing Rocks or Mountains in a 3×3 grid creates a Mountain Peak. This provides a larger max hp boost, as well as spawning Harpies. |
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Meadows | Placing Meadows next to anything creates a Blooming Meadow tile. This provides 3hp instead of 2hp per day. |
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Battlefield | Overlapping Battlefields create a Blood Path that spawns Blood Clots. |
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Village | Placing a Vampire Mansion next to a Village creates a Ransacked Village. This spawns four Ghouls for three loops before changing to a Count’s Lands tile. |
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Wheat Fields |
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Swamp | Placing a Swamp next to a Goblin Outpost creates a Goblin Lookout. |
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Grove |
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River |
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Forest | Placing a Forest or Thicket along a Storm Temple’s Path creates a Burned Forest. |
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Suburbs | Placing five Suburbs in a plus pattern creates a Town. | |
Abandoned Bookery |
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It’s possible more card combinations may be added to the game at a later time. Especially since there are two equipment slots that currently don’t have an item available for them. While there isn’t a roadmap for upcoming content, the developer has said they have “a lot of cool ideas” for the coming year.
If you have any questions regarding Loop Hero, feel free to ask in the comments below. And if you come across a new combination not mentioned in the article, let us know. Other useful Loop Hero guides here at Slyther Games are listed below.

Jeff is a journalist that loves to write, stream, and make content about video games. He’s a sucker for RPGs, survival games, roguelikes, and more.